Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797723 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 11 Pages |
Abstract
⺠The phospholemman cytoplasmic domain (PCD) interacts weakly with zwitterionic phospholipids. ⺠Phosphorylation of PCD at S68 lowers its phospholipid membrane affinity. ⺠PCD lowers the maximal rate of ATP hydrolysis by Na,K-ATPase. ⺠The inhibitory effect of PCD is partially relieved by phosphorylation at S68. ⺠The physical and functional properties of CHIF and Mat-8 cytoplasmic domains differ from PCD.
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Authors
Eleri Hughes, Christopher A.P. Whittaker, Igor L. Barsukov, Mikael Esmann, David A. Middleton,