Article ID Journal Published Year Pages File Type
10797723 Biochimica et Biophysica Acta (BBA) - Biomembranes 2011 11 Pages PDF
Abstract
► The phospholemman cytoplasmic domain (PCD) interacts weakly with zwitterionic phospholipids. ► Phosphorylation of PCD at S68 lowers its phospholipid membrane affinity. ► PCD lowers the maximal rate of ATP hydrolysis by Na,K-ATPase. ► The inhibitory effect of PCD is partially relieved by phosphorylation at S68. ► The physical and functional properties of CHIF and Mat-8 cytoplasmic domains differ from PCD.
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