Article ID Journal Published Year Pages File Type
10797725 Biochimica et Biophysica Acta (BBA) - Biomembranes 2011 10 Pages PDF
Abstract
► Microsolvation of bridging ion pairs in transmembrane helix dimers. ► Microsolvation in membrane core stabilizes ion pairs and H-bonds between TM helices. ► Position of charged/polar amino acids affects the degree of their hydration. ► Buried waters exchange with bulk waters on timescales of tens of nanoseconds. ► Similar findings for H-segment dimers and for E1-E2 dimers from HCV.
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