Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797725 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 10 Pages |
Abstract
⺠Microsolvation of bridging ion pairs in transmembrane helix dimers. ⺠Microsolvation in membrane core stabilizes ion pairs and H-bonds between TM helices. ⺠Position of charged/polar amino acids affects the degree of their hydration. ⺠Buried waters exchange with bulk waters on timescales of tens of nanoseconds. ⺠Similar findings for H-segment dimers and for E1-E2 dimers from HCV.
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Authors
Siti Azma Jusoh, Volkhard Helms,