| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797729 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 9 Pages |
Abstract
⺠Folate-targeted liposomes show enhanced ZnTPP internalization by receptor positive cells. ⺠Folate receptor deficient cells do not show variations in the liposomal incorporation. ⺠The photocytotoxicity induced by folate-targeted liposomes is improved. ⺠Both folate-targeted and non-targeted liposomes localize in acidic lysosomes. ⺠1O2 kinetics measured in living cells indicates a lysosome localization of ZnTPP.
Keywords
OOPSZnTPPPBSDMEMSDSFBSMLVPoPCD-PBSBCATHFPDT1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromideDMSODulbecco's modified Eagle's mediumMTTSinglet oxygenbicinchoninic acidTetrahydrofuranTargeted drug deliveryPhotodynamic therapyDimethyl sulfoxidesodium dodecyl sulfatefetal bovine serumPhotosensitizerLiposomesPhosphate-buffered salineMultilamellar vesicleFolate receptor
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
MarÃa GarcÃa-DÃaz, Santi Nonell, Ángeles Villanueva, Juan C. Stockert, Magdalena Cañete, Ana Casadó, Margarita Mora, M. Lluïsa Sagristá,