| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797733 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 11 Pages |
Abstract
⺠Membrane selectivity is shown for W/F-tagged short and highly charged peptides. ⺠These display broad-spectrum antimicrobial effect, but low toxicity to human cells. ⺠Parallel selectivity for anionic and cholesterol-void lipid membranes. ⺠Replacing cholesterol with ergosterol yields increased peptide-induced lysis. ⺠The generality of the membrane selectivity for related peptides is demonstrated.
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Authors
Artur Schmidtchen, Lovisa Ringstad, Gopinath Kasetty, Hiroyasu Mizuno, Mark W. Rutland, Martin Malmsten,