| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797741 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 9 Pages |
Abstract
⺠Human TRPA1 channel weakly discriminates among both mono- and divalent cations. ⺠PX+/PNa+s are Li+ (1.26) â¥Â K+ (0.98) â¥Â Rb+ (0.98) > Cs+ (0.95). ⺠PY2+/PNa+s are Ca2+ (5.1) > Ba2+ (3.5) > Mg2+ (2.8). ⺠Some ligands recruit the hTRPA1 channel to a state permeable to large organic cations. ⺠The pore of the channel in this state is dilated by approximately 1-2.5 Ã
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Y.V. Bobkov, E.A. Corey, B.W. Ache,