Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797749 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 7 Pages |
Abstract
⺠Daptomycin is shown to form oligomers on liposome membranes. ⺠Oligomerization depends on presence of phosphatidylglycerol; phosphatidylcholine membranes bind daptomycin but do not induce oligomerization. ⺠Lipid requirements for oligomerization correlate with those for antimicrobial activity.
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Authors
Jawad K. Muraih, Andre Pearson, Jared Silverman, Michael Palmer,