| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797753 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 9 Pages |
Abstract
⺠Gly3157.42 and Ser3197.46 stabilize β2-AR in an inactive conformation. ⺠Occluded surface calculations show Gly3157.42 does not form a water binding site. ⺠Gly3157.42 acts as a “molecular notch” to stabilize Trp2866.48 in an inactive position. ⺠Ser3197.46 mediates hydrogen bonding interactions between Trp2866.48 and Asn3227.49.
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Authors
Makoto Arakawa, Raja Chakraborty, Jasbir Upadhyaya, Markus Eilers, Philip J. Reeves, Steven O. Smith, Prashen Chelikani,