Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797869 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 8 Pages |
Abstract
⺠BAX α5-helix point mutations changed cholesterol-dependent insertion observed in the wild type protein. ⺠Substitutions in the BAX α5-helix sequence modified the protein channel properties. ⺠BAX pore activity was not dependent on cholesterol content in the membrane.
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Authors
Eduardo MartÃnez-Abundis, Francisco Correa, Emma RodrÃguez, Elizabeth Soria-Castro, José S. RodrÃguez-Zavala, Diana Pacheco-Alvarez, Cecilia Zazueta,