Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797881 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 6 Pages |
Abstract
⺠Biologically relevant sphingomyelin (SM) species are often asymmetric molecules. ⺠It is unclear how asymmetry affects interactions with cholesterol. ⺠We made SM analogs with saturated acyl chains which are 14 to 24 carbons long. ⺠We show that SM asymmetry affected sterol interaction. ⺠The most favorable interaction was seen between cholesterol and 16:0-SM.
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Authors
Shishir Jaikishan, J. Peter Slotte,