| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797889 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 8 Pages |
Abstract
⺠TM7 of the Na+/dicarboxylate cotransporter 1 is likely to be an outer helix. ⺠Gly-356 was inhibited by MTSET but could not be labeled by the bulkier MTSEA-biotin. ⺠Phe-336 and Phe-339 are important for substrate turnover or selectivity. ⺠TM7 contains functionally important residues; cysteine mutants had reduced activity independent of protein expression.
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Authors
Ana M. Pajor, Nina N. Sun, Aditya D. Joshi, Kathleen M. Randolph,