Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10798045 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 9 Pages |
Abstract
âºInfluenza M2 proton channel shows conformational plasticity due to the environment. âºThicker lipid membranes and drug binding promote kinked M2TM helices. âºChannel opening promotes a more ideal helical conformation at histidine-37. âºEquilibrium between different conformations is shifted by the environment.
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Authors
Fanghao Hu, Wenbin Luo, Sarah D. Cady, Mei Hong,