Global regulation of alternative RNA splicing by the SR-rich protein RBM39

Article ID	Journal	Published Year	Pages	File Type
10798911	Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms	2016	29 Pages	PDF

Abstract

The current study offers a genome-wide view of RBM39's regulatory function in alternative splicing. RBM39 may play important roles in multiple cellular processes by regulating both alternative splicing of RNA molecules and transcript levels.

Keywords

PNK KEGG serine/arginine-rich ULM Nonidet P-40 MXE U2AF65 A5SS A3SS RS domain NP-40 CLIP-seq RPKM UTRs snRNPs RRMs PBS SDS CEM FDR RT-PCR RNA-seq DEGs Alternative splicing Kyoto Encyclopedia of Genes and Genomes small nuclear ribonucleoproteins sodium dodecyl sulfate Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)Phosphate-buffered saline Untranslated regions false discovery rate ASD Gene ontology reverse transcription-polymerase chain reaction polynucleotide kinase Differentially expressed genes Estrogen receptor