| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10799210 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 8 Pages |
Abstract
In addition to their established crucial roles in the manipulation of RNA structure, it is becoming increasingly clear that several members of the DEAD box family act as regulators of transcription. In this review I shall focus on DDX5 (p68) and the highly related DDX17 (p72), two proteins for which there is a large body of evidence demonstrating that they function in transcriptional regulation. This article is part of a Special Issue entitled: The Biology of RNA helicases - Modulation for life.
Keywords
NF-κBnuclear factor of activated T-cells 5Brg-1Steroid receptor RNA activatorCP190NFAT5TFIIASRC-1P/CAFCTCFXIAPMAML1RNA helicaseVDRHDAC1PDGFGSK3βRUNX2Mcl-1PSACBPTBPERαRNA polymerase IIMyeloid cell leukemia-1Mdm2p53 upregulated modulator of apoptosisRNA pol IIProstate specific antigenBaxEMTDEAD boxSraCAMRunt-related transcription factor 2platelet-derived growth factornuclear factor-kappaBTRAILtumour necrosis factor-related apoptosis-inducing ligandTranscription regulationmouse double minute 2 homologhistone deacetylase 1Bcl-2-associated X proteinX-linked Inhibitor of Apoptosis ProteinCREB-binding proteinTATA binding proteinPUMAMulti-functionalBrahma-related gene 1CalmodulinEpithelial–mesenchymal transitionglycogen synthase kinase 3 betaAndrogen ReceptorSteroid receptor coactivator 1Estrogen receptor alphaVitamin D receptor
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Authors
Frances V. Fuller-Pace,