| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10799214 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 11 Pages |
Abstract
⺠The roles of accessory domains and proteins in helicase function are discussed. ⺠Helicases act as either general or mRNA-specific translation initiation factors. ⺠Direct and indirect effects of helicases on translation initiation are discussed. ⺠The helicase eIF4A cycles on and off the initiation complexes. ⺠DHX29 and other proteins could also cycle on and off the initiation complexes
Keywords
SF2ssDNARNA helicase ASSBuORFRHAUBAssRNARRMDDXtRNAEJCDEAD-boxmRNPPABPUpstream ORFDHxMet-tRNAiUTRssDNA-binding proteinmRNAPCEdsRBDORFRNA helicasedsRNAIRESSingle-stranded DNAeIFmessenger RNAsingle-stranded RNAdouble-stranded RNAtransfer RNATranslationUbiquitin-associated domainwinged helix domaininternal ribosome entry siteeukaryotic translation initiation factoropen reading frametranslation initiation factorinitiation complexExon junction complexuntranslated regionMicroRNAMiRNAwild typeDEAD-box proteinTernary complex
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Authors
Assen Marintchev,