Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10799224 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 10 Pages |
Abstract
⺠DExH/D box proteins are an under-appreciated family of drug targets. ⺠Conformational changes during catalysis provide for a myriad of compound target sites. ⺠eIF4A is a paradigm for selective pharmacological targeting by small molecules.
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Authors
Regina Cencic, Jerry Pelletier,