| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10799246 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 7 Pages |
Abstract
⺠TFIIB positions promoter DNA above the RNA polymerase II cleft. ⺠TFIIB guides descent of the template DNA strand into the polymerase cleft. ⺠TFIIB stabilizes an early transcribing complex. ⺠The fidelity of transcription is enhanced by the “trigger loop”. ⺠The translocation step may entail bending of the “bridge helix”.
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Authors
Xin Liu, David A. Bushnell, Roger D. Kornberg,