Article ID Journal Published Year Pages File Type
10799252 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2013 6 Pages PDF
Abstract
► Pol II must break promoter and factor interactions to enter transcript elongation. ► Abortive initiation is not extensive for pol II. ► Clearance is driven by TFIIH and collapse of the initial transcription bubble. ► Pol II early elongation complexes backtrack, even after RNA exits the polymerase. ► Clearance is incomplete until the pol II elongation complex is fully stabilized.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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