Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10799252 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 6 Pages |
Abstract
⺠Pol II must break promoter and factor interactions to enter transcript elongation. ⺠Abortive initiation is not extensive for pol II. ⺠Clearance is driven by TFIIH and collapse of the initial transcription bubble. ⺠Pol II early elongation complexes backtrack, even after RNA exits the polymerase. ⺠Clearance is incomplete until the pol II elongation complex is fully stabilized.
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Authors
Donal S. Luse,