Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10799257 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 11 Pages |
Abstract
⺠Spt4-Spt5 is a positive and negative regulator of transcription elongation. ⺠Spt5/NusG proteins are found in all organisms and are essential for life. ⺠Spt4-Spt5 links transcription elongation to chromatin remodeling and RNA processing. ⺠Structural studies are beginning to provide insights into Spt4-Spt5 function.
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Authors
Grant A. Hartzog, Jianhua Fu,