Article ID Journal Published Year Pages File Type
10799262 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2013 7 Pages PDF
Abstract
► Ubiquitylation and degradation of RNA polymerase II is a last resort pathway. ► Ubiquitylation occurs via a multi-step mechanism involving two distinct E3s and proofreading by ubiquitin proteases. ► The stopped form of RNA polymerase II is specifically targeted.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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