Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10799262 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 7 Pages |
Abstract
⺠Ubiquitylation and degradation of RNA polymerase II is a last resort pathway. ⺠Ubiquitylation occurs via a multi-step mechanism involving two distinct E3s and proofreading by ubiquitin proteases. ⺠The stopped form of RNA polymerase II is specifically targeted.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Marcus D. Wilson, Michelle Harreman, Jesper Q. Svejstrup,