Article ID Journal Published Year Pages File Type
10799269 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2013 7 Pages PDF
Abstract
► HNF-4 plays a crucial role in the development and maintenance the liver phenotype. ► Specific miRNAs down-regulate HNF-4 expression by targeting 3′-UTR of HNF-4 mRNA. ► The miRNA dependent regulation affects the transactivation of HNF-4 target genes. ► The regulatory mechanism of miRNAs may have important impacts on liver phenotype.
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Authors
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