Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10799273 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2013 | 11 Pages |
Abstract
⺠KSRP function is required to keep teratocarcinoma P19 cells in an undifferentiated state. ⺠KSRP favors the expression of two master regulators of neural differentiation. ⺠KSRP promotes the maturation of miR-200 family members from precursors. ⺠Maturation of miR-200 family members is reduced during P19 cell neural differentiation. ⺠KSRP silencing in P19 cells promotes the reshaping of their transcriptome.
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Authors
Matteo Giovarelli, Gabriele Bucci, Michela Pasero, Roberto Gherzi, Paola Briata,