Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10799282 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2012 | 7 Pages |
Abstract
⺠THO is a mRNP factor necessary for the formation of export-competent mRNAs. ⺠THO/TREX is recruited to all active RNAPII transcribed genes, accumulating towards the 3 â²end. ⺠THO and THSC/TREX-2 are two key mRNP with a role in the maintenance of genome integrity. ⺠THO is a dynamic factor transiently interacting with THSC/TREX-2, CIP29/Tho1 and related factors
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Authors
Rosa Luna, Ana G. Rondón, Andrés Aguilera,