Article ID Journal Published Year Pages File Type
10799282 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2012 7 Pages PDF
Abstract
► THO is a mRNP factor necessary for the formation of export-competent mRNAs. ► THO/TREX is recruited to all active RNAPII transcribed genes, accumulating towards the 3 ′end. ► THO and THSC/TREX-2 are two key mRNP with a role in the maintenance of genome integrity. ► THO is a dynamic factor transiently interacting with THSC/TREX-2, CIP29/Tho1 and related factors
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