Article ID Journal Published Year Pages File Type
10799283 Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2012 10 Pages PDF
Abstract
► Histone H2B ubiquitylation affects late mRNA export events. ► Ubiquitin regulates co-transcriptional recruitment of export factors. ► THO is a platform coordinating mRNP assembly, 3′ end formation and release from transcription sites. ► mRNP surveillance at the pore is linked to an ultimate remodeling step before exit into the cytoplasm. ► Ubiquitylation may regulate multiple aspects of nuclear pore complex structure and function.
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