Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10799283 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2012 | 10 Pages |
Abstract
⺠Histone H2B ubiquitylation affects late mRNA export events. ⺠Ubiquitin regulates co-transcriptional recruitment of export factors. ⺠THO is a platform coordinating mRNP assembly, 3Ⲡend formation and release from transcription sites. ⺠mRNP surveillance at the pore is linked to an ultimate remodeling step before exit into the cytoplasm. ⺠Ubiquitylation may regulate multiple aspects of nuclear pore complex structure and function.
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Authors
Anna Babour, Catherine Dargemont, Françoise Stutz,