Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10799286 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2012 | 9 Pages |
Abstract
⺠Transcript poly(A) tails of correct length are critical for proper gene expression. ⺠Nab2 is an essential nuclear polyadenosine binding protein in S. cerevisiae. ⺠Nab2 is important for control of poly(A) tail length of RNA transcripts. ⺠The Drosophila Nab2 homologue, dNab2, is critical for neuronal function in flies. ⺠Mutations in the gene encoding human Nab2, ZC3H14, cause intellectual disability.
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Authors
Sharon Soucek, Anita H. Corbett, Milo B. Fasken,