| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10799289 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2012 | 15 Pages |
Abstract
âºNuclear mRNA export begins with assembly of an export-competent mRNP in the nucleus. âºExport-competent mRNPs diffuse back-and-forth through nuclear pores. âºDbp5 removes export factors from mRNPs at the pore's cytoplasmic face, preventing return to the nucleus. âºTREX and TREX-2 link export-competent mRNPs assembly to earlier gene expression pathway steps. âºEmerging structural information is generating a molecular understanding of these processes.
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Authors
Eugene Valkov, Jack C. Dean, Divyang Jani, Sonja I. Kuhlmann, Murray Stewart,