Uroguanylin modulates (Na+Â +Â K+)ATPase in a proximal tubule cell line: Interactions among the cGMP/protein kinase G, cAMP/protein kinase A, and mTOR pathways

Article ID	Journal	Published Year	Pages	File Type
10799844	Biochimica et Biophysica Acta (BBA) - General Subjects	2016	25 Pages	PDF

Abstract

The current results expand our understanding of the signal transduction pathways involved in the overall effect of UGN on renal sodium excretion.

Keywords

GFR 8-Bromo-cyclic GMP dibutyryl cyclic AMP mTOR complex 2 Inhibitory G protein S6K NHE3 mTORC2 mTORC1 8-Br-cGMP PKG mTOR pKa db-cAMP PKB mTOR complex 1 S6 kinase Uroguanylin sodium reabsorption Cell signaling proximal tubule mammalian target of rapamycin protein kinase A protein kinase B protein kinase G Sodium pump Kidney

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Preview

Uroguanylin modulates (Na+Â +Â K+)ATPase in a proximal tubule cell line: Interactions among the cGMP/protein kinase G, cAMP/protein kinase A, and mTOR pathways

Authors

Francisco J. Arnaud-Batista, Diogo B. Peruchetti, Thiago P. Abreu, Nilberto R.F. do Nascimento, Gerhard Malnic, Manasses C. Fonteles, Celso Caruso-Neves,