Article ID Journal Published Year Pages File Type
10799929 Biochimica et Biophysica Acta (BBA) - General Subjects 2015 14 Pages PDF
Abstract
TQ is intercalated to human telomere G-quadruplex on two binding sites close to (a) T17, T18 and A19 loop with grid score of − 19.5 kcal/mol (low affinity site) and to (b) T11, T12 and A13 loop with grid score of − 26.2 kcal/mol (high affinity site). Docking of TQ on G-quadruplex structure using Dock 6.62
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Interaction of human telomeric G-quadruplex DNA with thymoquinone: A possible mechanism for thymoquinone anticancer effect
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