Free-radical first responders: The characterization of CuZnSOD and MnSOD regulation during freezing of the freeze-tolerant North American wood frog, Rana sylvatica

Article ID	Journal	Published Year	Pages	File Type
10799953	Biochimica et Biophysica Acta (BBA) - General Subjects	2015	10 Pages	PDF

Abstract

Augmented SOD activity may increase the ability of R. sylvatica to overcome oxidative stress associated with ischemia.

Keywords

PKC CuZnSOD Inositol trisphosphate Vmax PMSF pKa DEPC IP3 AMPK MnSOD TBST PKG PP1 PP2C NiSOD tris buffered saline with Tween nitrotetrazolium blue NBT PP2A IMAC PVDF KPI DTT MAPK ROS Antioxidant amyotrophic lateral sclerosis Ischemia ALS Freeze tolerance Oxidative stress Michaelis–Menten constant diethylaminoethyl cellulose polyvinylidene difluoride diethylpyrocarbonate dithiothreitol Rana sylvatica maximal velocity FeSOD phenylmethylsulfonyl fluoride Protein stability potassium phosphate protein phosphatase 1 protein phosphatase 2A protein phosphatase 2C protein kinase A protein kinase G Protein kinase C mitogen activated protein kinase 5′ adenosine monophosphate-activated protein kinase immobilized metal ion affinity chromatography Reactive oxygen species

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Free-radical first responders: The characterization of CuZnSOD and MnSOD regulation during freezing of the freeze-tolerant North American wood frog, Rana sylvatica

Authors

Neal J. Dawson, Barbara A. Katzenback, Kenneth B. Storey,