Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800035 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2015 | 11 Pages |
Abstract
The combination of structural and biochemical study has led to the detailed mechanistic understanding of this membrane spanning nano-machine. This can now be exploited to design novel drugs able to inhibit virulence. This is vital in the present era of resurgent antibiotic resistance. This article is part of a Special Issue entitled Structural biochemistry and biophysics of membrane proteins.
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Authors
James Lillington, Sebastian Geibel, Gabriel Waksman,