Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800084 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2014 | 8 Pages |
Abstract
This study provides understanding of hypoxia-mediated transcriptional regulation of arginase expression in the heart and its subsequent effect on eNOS activity, NO availability and signaling as well as cardiac oxidative stress. This information will support the use of arginase inhibitors as therapeutics for pathological hypoxia.
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Authors
Manjulata Singh, Gayatri Padhy, Praveen Vats, Kalpana Bhargava, Niroj Kumar Sethy,