Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800119 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2014 | 27 Pages |
Abstract
This review provides new information on the mechanisms regulating the state of differentiation of chondrocytes and the chondrogenesis of mesenchymal stem cells that will lead to the development of new restorative cell therapy approaches in humans. This article is part of a Special Issue entitled Matrix-mediated cell behaviour and properties.
Keywords
TGF-βMSCECMAGEsGAGIPSCPLAActivator protein-2BMPRAP-2HIFPGAHTRA1ADAMTSPLGAIGFNF-κBTNFPTHrPCbfa1/Runx2MMPROSSOxOsteoarthritisHyaluronic acidinterleukinHACtransforming growth factor-betaTriiodothyronineThyroxinESCcluster of differentiationBone marrow mesenchymal stem cellCell therapyinduced-pluripotent stem cellEmbryonic stem cellMesenchymal stem cellKeratan sulfateCartilageHypoxia-inducible factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Insulin-like growth factortumor necrosis factorNuclear factor-kappa BExtracellular matrixmatrix metalloproteinaseAdvanced glycation end productsBMPTissue engineeringNitric oxideProteoglycanParathyroid hormone-related proteinBone morphogenetic proteinpoly(glycolic acid)Poly(lactic acid)Poly(ε-caprolactone)polyethylene glycolPEGAutologous chondrocyte implantationaciChondrocyteChondroitin sulfateGlycosaminoglycanReactive oxygen speciesbone morphogenetic protein receptor
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Authors
Magali Demoor, David Ollitrault, Tangni Gomez-Leduc, Mouloud Bouyoucef, Magalie Hervieu, Hugo Fabre, Jérôme Lafont, Jean-Marie Denoix, Fabrice Audigié, Frédéric Mallein-Gerin, Florence Legendre, Philippe Galera,