| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800193 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2014 | 9 Pages |
Abstract
This review highlights our understanding of how exercise positively impacts skeletal muscle mitochondrial biogenesis and function. Exercise not only improves skeletal muscle mitochondrial health but also enables us to identify molecular mechanisms that may be attractive targets for therapeutic manipulation. This article is part of a Special Issue entitled Frontiers of mitochondrial research.
Keywords
BNIP3cox2CaMKFOXO3aPINK1NRF-2tRNAT2DCoQSOD1PGC-1αDMDCOX1Drp1NRF-1TFAMSIRT-1MFN2PGC-1AMPKMEF2ChttMfn1Sirtuin-1COX4CREBMUL1AICARTNFαERRαmiRNAsNF90PGC-1βmRNArRNABCL2/adenovirus E1B 19 kDa interacting protein 3FOXJ3PDK4Myocyte enhancer factor 2CATF-2sequestosome 1HDACPPARAMP-activated protein kinaseMitochondrial DNAopa1p38 MAPKp62/SQSTM1PTEN-induced putative kinase 1messenger RNARibosomal RNAROSoptic atrophy 1IBMtransfer RNAAlzheimer’s diseaseHuntington’s diseaseNeuromuscular diseaseParkinson's diseasetumour necrosis factor alphaType 2 diabetesDuchenne muscular dystrophymtDNAmicroRNAsMitochondrial biogenesisthree prime untranslated regionNuclear respiratory factor 1nuclear respiratory factor 2mitochondrial transcription factor ASkeletal muscleactivating transcription factor-2mitofusin 1mitofusin 2Inclusion-body myositisNitric oxideHuntingtinhistone deacetylaseexerciseParkincAMP-response element-binding proteinp38 mitogen-activated protein kinaseCoenzyme QReactive oxygen speciesperoxisome proliferator-activated receptor
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Authors
Aaron P. Russell, Victoria C. Foletta, Rod J. Snow, Glenn D. Wadley,