Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800213 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2014 | 18 Pages |
Abstract
In the context of current structural data we review the structural details of the interfaces and recognition sites in complexes of sub-family A GPCRs with cognate G-proteins, with special emphasis on the consequences of activation on GPCR structure, the prevalence of preassembled GPCR/G-protein complexes, the key structural determinants for selective coupling and the possible involvement of GPCR oligomerization in this process.
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Authors
Irina S. Moreira,