Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800348 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2014 | 10 Pages |
Abstract
Our observations suggest the semi-synthetic ent-kaurane SC2017 as a promising chemotherapeutic compound. SC2017 has, indeed, shown to possess tumor growth inhibiting activity and be able to counteract PI3K/Akt and Trx system survival signaling.
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Authors
Roberta Cotugno, Dario Gallotta, Fabrizio Dal Piaz, Ivana Apicella, Sandro De Falco, Sergio Rosselli, Maurizio Bruno, Maria Antonietta Belisario,