Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800432 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 15 Pages |
Abstract
⺠Novel functions of GPx1-8 regarding the essential physiological functions of ROS ⺠Balancing levels of H2O2 in, e.g., insulin signalling by GPx1 ⺠The role of GPx2 in cancer depends on the mode of initiation and cancer stage ⺠Specific roles of GPx4 in apoptosis and together with GPx5 in male fertility ⺠Downregulation as well as overexpression of GPxs can have harmful effects.
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Authors
Regina Brigelius-Flohé, Matilde Maiorino,