Article ID Journal Published Year Pages File Type
10800529 Biochimica et Biophysica Acta (BBA) - General Subjects 2013 30 Pages PDF
Abstract
The comprehension of molecular mechanisms that modulate the intersection between these proteins will be important to identify new signaling axis involved in lifespan extension as well as novel targets for therapeutic interventions.
Keywords
Sirt1CREBSOD1PGC-1αPPARαTFAMNRF1SOD2RNSBATRARPPARγETsGPx1NFE2L2OXPHOSGSHTFEBNADPHPRXcap ‘n’ collarγGCSNEHp53MEF2COXCNCHOSCu,Zn superoxide dismutasePPARsROSbrown adipose tissueHuntington's diseaseParkinson's diseaseTranscriptional regulationMitochondrial biogenesisMn superoxide dismutasecytochrome c oxidasemyocyte enhancer factor-2Nuclear respiratory factor 1Transcription factor EBmitochondrial transcription factor Aantioxidant responsive elementFoxOOxidative phosphorylationcalorie restrictionnicotinamide adenine dinucleotide phosphate-oxidaseAREheme oxygenasePARISAntioxidant responsetumor protein 53cAMP response element-binding proteinPeroxiredoxinGamma-glutamylcysteine synthetaseGlutathioneGlutathione peroxidasesreactive nitrogen speciesReactive oxygen speciesRetinoic acid receptorperoxisome proliferator-activated receptorestrogen-related receptorperoxisome proliferator-activated receptor γperoxisome proliferator-activated receptor α
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Punctum on two different transcription factors regulated by PGC-1α: Nuclear factor erythroid-derived 2-like 2 and nuclear respiratory factor 2
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