| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800557 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 11 Pages |
Abstract
⺠The glucose-6-phosphatase (G6PC) gene family presently includes three members. ⺠G6PC isoforms show similar intracellular location, membrane topology and catalytic site. ⺠G6PC isoforms function as glucose producer, glucose sensor or antiapoptotic factor. ⺠Mutations of G6PCs are associated with human diseases.
Keywords
NODFGLG6PTRORαPEPCKG6PCG6PDiabetesSmall intestineendoplasmic reticuluminorganic phosphatephosphoenolpyruvate carboxykinasenon-obese diabetic miceCongenital neutropeniaGlycogen storage disease type 1Single-nucleotide polymorphismsSNPglucose-6-phosphateglucose-6-phosphate transporterglucose-6-phosphataseGlucokinaseGlycemia
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Authors
Paola Marcolongo, Rosella Fulceri, Alessandra Gamberucci, Ibolya Czegle, Gabor Banhegyi, Angelo Benedetti,