| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800560 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 9 Pages |
Abstract
⺠Gemcitabine (GEM) suppressed growth in the human pancreatic cancer cell lines. ⺠Spinach monogalactosyl diacylglycerol (MGDG) suppressed cancer cell growth. ⺠GEM-MGDG combination revealed synergistic effects on the cancer cell growth. ⺠These enhancements might cause the inhibition of mammalian DNA polymerase. ⺠MGDG from spinach could be an effective clinical anticancer chemotherapy of GEM.
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Authors
Hiroaki Akasaka, Ryohei Sasaki, Kenji Yoshida, Izumi Takayama, Toyofumi Yamaguchi, Hiromi Yoshida, Yoshiyuki Mizushina,