Article ID Journal Published Year Pages File Type
10800586 Biochimica et Biophysica Acta (BBA) - General Subjects 2013 9 Pages PDF
Abstract
► Skeletal muscle from cachectic animals showed fiber morphologic alterations. ► These alterations are mitochondrial disruption and dilatation of sarcoplasmic reticulum. ► An overexpression of both sarco/endoplasmic Ca2 +-ATPase (SERCA1) and adenine nucleotide translocator (ANT1) was reported. ► Tumor burden also leads to a marked decreased in muscle ATP content.
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