| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800587 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 11 Pages |
Abstract
⺠Celastrol induces apoptosis in HeLa cells by ÎΨmâ and capase-3 activation. ⺠Celastrol down-regulates HeLa cells' energy, amino acids and nucleic acid metabolism. ⺠Metabolomic investigation on celastrol is validated using positive control drugs. ⺠GC/MS-based metabolomic approach elucidates celastrol's pharmacological mechanism.
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Authors
Yongsheng Hu, Yunpeng Qi, Hua Liu, Guorong Fan, Yifeng Chai,