| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800594 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 14 Pages |
Abstract
⺠Alkaline phosphatase (ALP) is a direct target gene of Runx2. ⺠Nuclear matrix-targeting of Runx2 is essential for its recognition of ALP. ⺠Nuclear matrix-targeting of Runx2 is essential for its activation of ALP. ⺠Runx2K120A accumulates largely in the nuclear matrix fraction. ⺠Runx2K120A hampers the activation of ALP by wild-type Runx2.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Jing-jie Weng, Yeu Su,