Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800600 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 6 Pages |
Abstract
⺠Mouse models allow assessment of the role of CoRs in NR signaling. ⺠CoRs mediate repression of positive targets by TR in the absence of T3. ⺠CoRs play a role in establishing a set point of HPT axis. ⺠CoRs attenuate transcriptional activity of NRs in the presence of ligands. ⺠CoR might be new drug targets for endocrine and metabolic disorders.
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Authors
Inna Astapova, Anthony N. Hollenberg,