Article ID Journal Published Year Pages File Type
10800600 Biochimica et Biophysica Acta (BBA) - General Subjects 2013 6 Pages PDF
Abstract
► Mouse models allow assessment of the role of CoRs in NR signaling. ► CoRs mediate repression of positive targets by TR in the absence of T3. ► CoRs play a role in establishing a set point of HPT axis. ► CoRs attenuate transcriptional activity of NRs in the presence of ligands. ► CoR might be new drug targets for endocrine and metabolic disorders.
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