| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800601 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 11 Pages |
Abstract
⺠Thyroid hormones induce metamorphosis that mimics the perinatal period in mammals. ⺠Amphibians provide an excellent model to analyze thyroid hormone receptor action. ⺠Thyroid hormone receptors act on gene expression through coregulators recruitment. ⺠Thyroid hormone receptor can change the chromatin structure and histone modifications. ⺠A model that highlights the diversity of thyroid hormone effects could be proposed.
Keywords
SMRTCBPBrg1HDMEZH2RXRhMTCARM1ME2NCoRPRMT1X. laevisme3X. tropicalisXenopus leavisenhancer of Zeste 2TBL1SRCXenopus tropicalisHDACTRAPArginineHistone modificationchromatin immunoprecipitationChromatin remodelingTranscriptional regulationCoregulatoreverted repeatdirect repeatAmphibian metamorphosisdimethylTREdominant negativeDripArcLysinenuclear receptor corepressorThyroid hormoneHistone H3Histone H4Histone acetyltransferasehistone deacetylasehistone demethylaseHistone Methyltransferaseprotein arginine methyltransferase 1CHiPHATsteroid receptor coactivatorthyroid hormone receptor
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Authors
Alexis Grimaldi, Nicolas Buisine, Thomas Miller, Yun-Bo Shi, Laurent M. Sachs,