| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800608 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 10 Pages |
Abstract
⺠The type 3 deiodinase inactivates thyroid hormones thus limiting their action. ⺠D3 plays important roles during development and in adult physiology. ⺠The D3 gene is imprinted and preferentially expressed from the paternal allele. ⺠Dlk1-Dio3 locus genomic elements and epigenetic marks direct Dio3 allelic expression. ⺠Altered imprinted gene dosage in the Dlk1-Dio3 cluster causes abnormal phenotypes.
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Authors
Marika Charalambous, Arturo Hernandez,