Article ID Journal Published Year Pages File Type
10800612 Biochimica et Biophysica Acta (BBA) - General Subjects 2013 8 Pages PDF
Abstract
► Thyroid hormones regulate bone development, peak bone mass and adult bone turnover. ► Thyroid hormone deficiency and excess are associated with increased fracture risk. ► Euthyroid status is essential for normal bone development and maintenance. ► TRα mediates the major actions of T3 in the skeleton. ► T3 exerts anabolic effects during growth but catabolic action in the adult skeleton.
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