| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800633 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 13 Pages |
Abstract
⺠First report of high mass thrombin-like serine protease from Russell's Viper venom ⺠Preferentially releases FPA from fibrinogen, producing hypofibrinogenemia ⺠Extensive post-translational glycosylation protecting against endogenous inhibitors ⺠Non-toxic to mice and shows in vitro and in vivo defibrinogenating activity ⺠High potential for use as a defibrinogenating drug and/or for drug design
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Authors
Ashis K. Mukherjee, Stephen P. Mackessy,