| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800648 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 10 Pages |
Abstract
⺠Zoledronate suppresses precursor osteoclast maturation and osteolytic activity. ⺠Modulates the expression of matrix macromolecules implicated in adhesion and bone osteolysis ⺠Potential inhibitor of breast cancer-mediated osteolysis
Keywords
MT-MMPCatKTissue inhibitors of MMPsPTHrPM-CSFOPGECMNTXBPSMMPZoledronateRANKLOsteoprotegerinBisphosphonatesTIMPZOLBreast cancerExtracellular matrixmatrix metalloproteinasemacrophage colony-stimulating factorBone metastasisMetalloproteinaseCellular modelParathyroid hormone-related peptideCathepsin Kreceptor activator of nuclear factor-κB ligand
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Authors
P.G. Dedes, I. Kanakis, Ch. Gialeli, A.D. Theocharis, T. Tsegenidis, D. Kletsas, G.N. Tzanakakis, N.K. Karamanos,