| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800651 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 6 Pages |
Abstract
⺠STAT3 induces serum amyloid A1 (SAA1) gene expression via the IL-6 transduction. ⺠No recognizable STAT3-RE is characterized near the NF-κB RE in the SAA gene promoters. ⺠A computational method was used to identify non-consensus STAT3-REs in SAA1 promoter. ⺠The candidates were evaluated with dual-luciferase reporter and DNA binding assays. ⺠By recognizing a wider array of REs, STAT3 may regulate a larger number of targets.
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Authors
Prabha Tiwari, Lokesh P. Tripathi, Teppei Nishikawa-Matsumura, Shandar Ahmad, Soken-Nakazawa J. Song, Tomoyasu Isobe, Kenji Mizuguchi, Kazuyuki Yoshizaki,