| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800658 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 11 Pages |
Abstract
⺠Mn(II) binds to the A site of the binuclear K. radiotolerans Dps ferroxidase center. ⺠A heterometallic ferroxidase center is formed when Fe(II) binds to the B site. ⺠During the catalyzed Fe(II) oxidation Mn(II) participates in redox cycling. ⺠Both the Mn/Fe and the canonic Fe/Fe ferroxidase centers limit OH release in solution. ⺠Mn(II) participation in redox cycling of KrDps may explain the Mn-dependent protection against oxidative stress.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Matteo Ardini, Annarita Fiorillo, Maria Fittipaldi, Simonetta Stefanini, Dante Gatteschi, Andrea Ilari, Emilia Chiancone,