Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800674 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 16 Pages |
Abstract
⺠Notch signaling is important during development and in adult stem cells. ⺠We review receptor and ligand structure and mechanisms of regulation. ⺠Control of target gene expression and cell fate output are discussed. ⺠Finally, we give an in-depth description of Notch's function in adult stem cells.
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Authors
Carolina N. Perdigoto, Allison J. Bardin,