Article ID Journal Published Year Pages File Type
10800674 Biochimica et Biophysica Acta (BBA) - General Subjects 2013 16 Pages PDF
Abstract
► Notch signaling is important during development and in adult stem cells. ► We review receptor and ligand structure and mechanisms of regulation. ► Control of target gene expression and cell fate output are discussed. ► Finally, we give an in-depth description of Notch's function in adult stem cells.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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